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Title: [Effect of premedication and fentanyl administration on the endocrine stress reaction during halothane anesthesia]. Author: Adams HA, Russ W, Börner U, Gips H, Hempelmann G. Journal: Anasth Intensivther Notfallmed; 1987 Jun; 22(3):118-23. PubMed ID: 3631465. Abstract: The influence of two different premedication regimens (diazepam versus pethidine/promethazine with fentanyl substitution before induction) on the endocrine stress-response during halothane anaesthesia was investigated in twenty orthopedic surgery patients. After premedication, the levels of plasma catecholamines, ADH, ACTH and cortisol were lower in the pethidine/promethazine-than in the diazepam-group. The levels of adrenaline remained significantly lower during the whole observation period. Thirty minutes after extubation all endocrine parameters except noradrenaline were lower in the pethidine/promethazine-group than in the diazepam-group.[Abstract] [Full Text] [Related] [New Search]