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  • Title: [Craniofacial growth under the influence of blood supply. 5. Brain weight after unilateral interruption of the common carotid artery].
    Author: Köster D, Mierzwa J, Schumacher GH, Fanghänel J.
    Journal: Anat Anz; 1987; 163(4):323-6. PubMed ID: 3631526.
    Abstract:
    After unilateral ligature of the common carotid artery in rats aged 42 d, the fresh weight of the brain does not deviate from that associated with normal growth in the course of subsequent postnatal development. This is believed to be due to the age at which the ligature was applied and to arterial compensatory mechanisms. The sensitive phases of cerebral development have already come to an end 42 d post partum. Ligature of the right common carotid artery can be fully compensated by circulus arteriosus (Willis), which provides hemodynamic pressure compensation.
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