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  • Title: Drug-specific Fab therapy in drug overdose.
    Author: Hursting MJ, Raisys VA, Opheim KE.
    Journal: Arch Pathol Lab Med; 1987 Aug; 111(8):693-7. PubMed ID: 3632280.
    Abstract:
    The use of digoxin-specific fragments, antigen-binding (Fab) for antidotal therapy of severe digitalis intoxication is rapidly becoming a treatment of choice. Furthermore, studies with this mode of drug-specific therapy using Fab specific for desipramine and for phencyclidine suggest that this treatment may be applicable to a variety of other drugs or drug classes. As Fab technology has advanced, so have laboratory methods for monitoring the efficacy of treatment.
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