These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Transport of p-aminohippurate in renal cortical slices of rats of different ages following treatment with thyroid hormones.
    Author: Bräunlich H.
    Journal: Biomed Biochim Acta; 1987; 46(4):251-7. PubMed ID: 3632649.
    Abstract:
    Following treatment with thyroid hormones PAH accumulation is increased in renal cortical slices of 5-, 10-, 20-, 30-, 50- and 105-day-old rats. Both thyroid hormones are more effective in young than in adult rats. A single dose of T3 or T4 (20 micrograms/100 g b.m.) administered 24 h before measurement is effective whereas acute effects of T3 or T4 on PAH transport could not be demonstrated. Treatment with thyroid hormones (20 micrograms/100 g b.m., 3 days, once a day) is without any influence on body mass; there is a tendency to an increase of kidney mass following treatment with T3 or T4. Simultaneous administration of an inhibitor of protein biosynthesis (neomycin, 1 or 5 mg/100 g b.m.) reduces the effect of T3 treatment. An additional low dose of T3, 24 h before measurement of PAH transport can restore the effect of T3 treatment which was performed 9 days before.
    [Abstract] [Full Text] [Related] [New Search]