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  • Title: Effects of kallidinogenase on urinary kallikrein excretion and plasma prostanoid concentrations in patients with essential hypertension.
    Author: Ogawa K, Ito T, Ban M, Motizuki M, Satake T.
    Journal: Experientia; 1986 Sep 15; 42(9):1014-5. PubMed ID: 3639011.
    Abstract:
    The effects of kallidinogenase on urinary kallikrein excretion, plasma immunoreactive prostanoids and platelet aggregation were investigated in patients with essential hypertension. Urinary kallikrein excretion and plasma 6-keto PGF1 alpha concentration were significantly decreased in these patients. Significant decreases in blood pressure, as well as significant increases of urinary kallikrein excretion and plasma 6-keto PGF1 alpha concentration after kallidinogenase administration were also observed.
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