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  • Title: Somatic O-1 antigen conversion of Salmonella typhimurium by a type B phage P221dis, hybrid between P22 and Fels 1 phages.
    Author: Yamamoto N.
    Journal: J Gen Virol; 1978 Nov; 41(2):367-76. PubMed ID: 363976.
    Abstract:
    A type B Salmonella phage P221, derived from recombination between a type A phage P22 and a type B phage Fels 1, carries the protein coat of Fels 1 and the P22 early genes, at least the c to h21 genes. One of the P221 strains, P221dis, is dismune over P221 lysogens and co-immune with P22. Thus it carries the Im gene (the second immunity region) of P22 to establish co-immunity with P22. Since the att region and a1 gene for somatic 0--1 antigen conversion of P22 are located between the Im and c genes, the P221dis prophage attachment site and 0--1 antigen of P221dis lysogens were analysed. P221dis prophage is integrated at the attP22 site near the pro A region of the bacterial chromosomes and expresses the somatic 0--1 antigen.
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