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  • Title: [Current treatment and advances of skull base osteoradionecrosis for nasopharyngeal carcinoma].
    Author: Mao S, Tang R, Liu SX, Li ZP, Ye HB, Zhang WT.
    Journal: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2022 Nov 07; 57(11):1354-1358. PubMed ID: 36404665.
    Abstract:
    放射性颅底骨坏死（skull base osteoradionecrosis，sbORN）是鼻咽癌放疗后的严重并发症之一，显著影响患者生存时间与生活质量。sbORN及其导致的颈内动脉（internal carotid artery，ICA）破裂大出血，是影响患者5年总体生存率的独立危险因素。该病临床疗效欠佳，是目前鼻咽癌临床诊疗的难点，加之颅底结构复杂，包括ICA、颅神经等重要结构，一旦发生则临床危害巨大。本文拟归纳总结近年来国内外关于鼻咽癌sbORN的治疗现状与进展，旨在为该病的治疗提供临床参考。.
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