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  • Title: [Use of clofelin for arresting hypertensive crises].
    Author: Anshelevich IuV, Raĭbart IaIa, Panov IP, Zveĭnietse RA, Orshanskiĭ EM.
    Journal: Kardiologiia; 1978 Nov; 18(11):102-5. PubMed ID: 364159.
    Abstract:
    The authors gave clophelin by intravenous (0.1 g) or intramuscular (0.1--0.15 mg) injections to 75 patients who were in a state of hypertensive crisis. In 67 patients (89--4%) the crisis was successfully arrested. In most patients maximum hypotensive effect occurred 10--20 minutes after intravenous injection and 20--30 minutes after intramuscular administration. Tolerance to a single injection of the drug was good. In some cases there was a marked additional fall of arterial pressure in the orthostatic position, a sensation of dryness in the mouth, weakness and mild somnolence.
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