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  • Title: Chloramphenicol-resistant Salmonella typhi in Durban, South Africa.
    Author: Coovadia YM, Van den Ende J.
    Journal: Trop Geogr Med; 1987 Jan; 39(1):64-6. PubMed ID: 3649097.
    Abstract:
    A retrospective survey was undertaken to determine the incidence of chloramphenicol-resistant Salmonella typhi in Durban, South Africa. Of the 3313 strains tested over a 7 year period 20 (0.6%) showed intermediate resistance to chloramphenicol and 19 (0.6%) were fully resistant. Resistance to chloramphenicol was found to fluctuate over the period studied (0-2%). Resistance to ampicillin/amoxycillin was encountered less frequently (0-0.9%). For the present we would still recommend chloramphenicol or amoxycillin for the initial treatment of typhoid fever in this region.
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