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Title: Gastrin cell populations after highly selective vagotomy in the dog. Author: Dunn DH, Decanini C, Bonsack ME, Eisenberg MM, Delaney JP. Journal: Am J Surg; 1979 Jan; 137(1):111-5. PubMed ID: 365007. Abstract: Highly selective vagotomy was performed on five dogs. Postoperatively, gastrin cell (G cell) hyperplasia occurred in all dogs. Mean preoperative G cell numbers increased from 350 to 530/cm mucosal length (p less than 0.02). Antral tissue gastrin also increased by 100 per cent (6.7 x 10(6) to 13.7 x 10(6) pg/gm tissue, p less than 0.05). Basal and stimulated serum gastrin were unchanged following highly selective vagotomy. The cause for G cell hyperplasia is not clear, but is probably multifactorial.[Abstract] [Full Text] [Related] [New Search]