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  • Title: Two new dammarane-type saponins from radix and rhizomes of Panax ginseng C. A. Meyer.
    Author: Niu X, Shi Y, Teng L, Lv C, Lu J.
    Journal: Nat Prod Res; 2024 May; 38(9):1463-1470. PubMed ID: 36503373.
    Abstract:
    Two new dammarane-type ginsenosides elucidated as 6-O-[α-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl]-dammar-24-ene-3β, 6α, 12β, 20S-tetraol, named 20(S)-Ginsenoside Re10 (4); 6-O-[α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl]-20-O-[α-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl]-dammar-24-ene-3β, 6α, 12β, 20R-tetraol, named 20(R)-Ginsenoside Re11 (8); along with one steroidal saponin (1) and six known triterpenoid ginsenosides (2, 3, 5, 6, 7 and 9) were isolated from the radix and rhizomes of mountain-cultivated ginseng (Panax ginseng C. A. Meyer, family Araliaceae). Their structures were determined by comprehensive chemical and spectroscopic analysis. In addition, what's even more concerning is that protodioscin was isolated for the first time from Panax ginseng.
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