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  • Title: The effect of pirozadil on plasma lipids and lipoproteins in 1185 hyperlipidaemic subjects. Multicentre study in general practice in Spain.
    Author: Tapounet R, Marti Ragué I.
    Journal: Drugs Exp Clin Res; 1987; 13(7):447-50. PubMed ID: 3652931.
    Abstract:
    The lipid-lowering agent pirozadil was tested in 1185 hyperlipidaemic subjects during a 2-4 months' intake. Plasma triglycerides were found to decrease by 30.8%. The reduction of plasma cholesterol (by 20.8%) was mainly due to a fall in low-density lipoprotein cholesterol by 23.7%, while high-density lipoprotein cholesterol increased up to 32.2%. Pirozadil was effective and well-tolerated in patients with both hypercholesterolaemia and hypertriglyceridaemia.
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