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  • Title: Highly stretchable, adhesive, and biocompatible hydrogel platforms of tannic acid functionalized spherical nanocellulose for strain sensors.
    Author: Patel DK, Ganguly K, Dutta SD, Patil TV, Randhawa A, Lim KT.
    Journal: Int J Biol Macromol; 2023 Feb 28; 229():105-122. PubMed ID: 36587632.
    Abstract:
    The development of multifunctional wearable electronic devices has received considerable attention because of their attractive applications. However, integrating multifunctional abilities into one component remains a challenge. To address this, we have developed a tannic acid-functionalized spherical nanocellulose/polyvinyl alcohol composite hydrogel using borax as a crosslinking agent for strain-sensing applications. The hydrogel demonstrates improved mechanical and recovery strengths and maintains its mechanical strength under freezing conditions. The hydrogels show ultra-stretching, adhesive, self-healing, and conductive properties, making them ideal candidates for developing strain-based wearable devices. The hydrogel exhibits good sensitivity with a 4.75 gauge factor. The cytotoxicity of the developed hydrogels was monitored with human dermal fibroblast cells by WST-8 assay in vitro. The antibacterial potential of the hydrogels was evaluated using Escherichia coli. The hydrogels demonstrate enhanced antibacterial ability than the control. Therefore, the developed multifunctional hydrogels with desirable properties are promising platforms for strain sensor devices.
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