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  • Title: Primary ciliary dyskinesia and nasal mucociliary clearance.
    Author: van der Baan S, Veerman AJ, Heidendahl GA, den Hollander W, Feenstra L.
    Journal: Respiration; 1987; 52(1):69-75. PubMed ID: 3659586.
    Abstract:
    In this study, nasal mucociliary clearance is investigated in patients with primary ciliary dyskinesia, patients with other respiratory tract infections and healthy persons. Mucociliary clearance is established with a drop of albumen labelled with 99m-Tc. From this study it appears that measurement of mucociliary clearance in the nose can serve as a reliable screening method. If a patient with respiratory tract infections shows a normal mucociliary clearance rate there is no primary ciliary dyskinesia, and a biopsy of ciliated epithelium is not necessary. If, after repeated examinations, a normal clearance rate cannot be demonstrated, a biopsy of ciliated epithelium should be taken for studying ciliary activity and ciliary ultrastructure.
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