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  • Title: Laboratory transmission of lymphatic filariasis by vector mosquitoes.
    Author: Ewert A, Wu CC, Fan PC.
    Journal: Southeast Asian J Trop Med Public Health; 1987 Mar; 18(1):73-8. PubMed ID: 3660071.
    Abstract:
    Aedes togoi and Ae. aegypti were used to examine the transmission potential of Brugia pahangi to one of its natural hosts, the domestic cat. Although a larger proportion of microfilariae taken in by Ae. togoi developed into infective larvae, the total number of B. pahangi larvae recovered from a cat exposed to Ae. aegypti was larger than from a cat exposed to Ae. togoi. Factors influencing the transmission dynamics included: development of microfilariae to infective larvae; survival of mosquitoes; willingness to take repeated blood meals; and proportion of infective larvae that egress from mosquitoes during the feeding process. From 19 to 25% of infective larvae were transferred to a susceptible host. The feasibility of using a Brugia-cat model to do comparative vector efficiency studies was demonstrated.
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