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  • Title: Taxotrophises A and B, two new polyphenols from the stems of Taxotrophis ilicifolius.
    Author: Do TNV, Nguyen HX, Le TH, Dang PH, Nguyen NT, Nguyen MTT.
    Journal: Nat Prod Res; 2024 Jul; 38(13):2187-2192. PubMed ID: 36606539.
    Abstract:
    From the EtOAc extract of the wood of the stems of Taxotrophis ilicifolius (Moraceae), two new secondary metabolites, named taxotrophises A (1) and B (2), were isolated, together with five known compounds (3-7). Their chemical structures have been elucidated by extensive NMR spectroscopic analysis. All isolated compounds have been evaluated for α-glucosidase inhibitory activity. In the present work, compounds 1 and 4 showed the strongest α-glucosidase inhibitory activity with IC50 values of 6.5 and 1.5 μM, respectively, and stronger than that of a positive control, acarbose (IC50; 214.5 μM).
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