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  • Title: Peripheral blood and bone marrow abnormalities in the acquired immunodeficiency syndrome.
    Author: Frontiera M, Myers AM.
    Journal: West J Med; 1987 Aug; 147(2):157-60. PubMed ID: 3660772.
    Abstract:
    In reviewing the peripheral hematologic manifestations, bone marrow changes and clinical course in 41 consecutive patients with acquired immunodeficiency syndrome (AIDS), frequent findings included anemia (95%), leukopenia (76%), bone marrow hypercellularity (73%) and pancytopenia (41%). These hematologic abnormalities were not clearly associated with specific clinical manifestations of AIDS, but support the conclusion that the hematopoietic system is a target organ in AIDS. The mechanisms of these abnormalities still need to be evaluated. Clinicians should be aware of these commonly encountered changes.
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