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  • Title: The effect of a lipid suspension on amitriptyline disposition.
    Author: Minton NA, Goode AG, Henry JA.
    Journal: Arch Toxicol; 1987 Aug; 60(6):467-9. PubMed ID: 3662823.
    Abstract:
    A 5-h infusion of a lipid suspension or saline was given on separate occasions to four healthy volunteers taking amitriptyline. Mean plasma levels of amitriptyline plus nortriptyline were 14% higher at the end of the lipid infusion but the difference was not statistically significant. Infusion of a lipid suspension is unlikely to materially affect the severity of amitriptyline intoxication.
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