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  • Title: [Practical recommendations for examining the pulmonary pleura of fetuses and newborn infants using contact microscopy].
    Author: Andreeva TV.
    Journal: Arkh Patol; 1987; 49(7):80-2. PubMed ID: 3662866.
    Abstract:
    It has been found that the pleura visceralis of fetuses and neonates is consistently involved in inflammatory processes occurring in pneumonias caused by Gram-negative organisms (Citrobacter sp., Escherichia coli, Klebsiella sp., Serratia marcescens) and may display signs of infection when the pneumonia is not yet apparent. This property of the pleura as a filtration membrane may help the pathologist in the early diagnosis of infectious disorders in neonates. Recommendations are given on the excision of pulmonary pleura and the staining of its preparations for contact microscopy whereby these can be examined during or shortly after the autopsy. Morphologic features of the infections caused by the indicated organisms are detailed. Citrobacter infections, for example, show a preponderance of macrophage responses, Klebsiella-caused lesions are characterized by involvement of the lymphatic bed, while those due to S. marcescens have hemolysis in the lung tissue and pleura as their main feature.
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