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  • Title: Liver microsomal membrane fluidity and lipid characteristics in vitamin A-deficient rats.
    Author: Hamm MW, Chan V, Wolf G.
    Journal: Biochem J; 1987 Aug 01; 245(3):907-10. PubMed ID: 3663201.
    Abstract:
    Rat liver microsomes (microsomal fraction) were isolated from vitamin A-deficient and -sufficient rats and analysed for membrane lipid characteristics. Membrane fluidity was found to be significantly decreased in microsomes from the vitamin A-deficient rats, but not in liposomes prepared from lipid extracts. Microsomes from vitamin A-deficient animals showed a significant decrease in C18:2, omega 6 and an increase in C22:5, omega 6 fatty acids.
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