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  • Title: Vertebromedular histoplasmosis: About a case of transverse myelitis in a young and immunocompetent adult.
    Author: Ngo Pambe CJ, Aminou M, Ngaroua, Mendimi Nkodo JM.
    Journal: Indian J Pathol Microbiol; 2023; 66(1):196-198. PubMed ID: 36656241.
    Abstract:
    Systemic mycosis raging endemic, histoplasmosis has an increasing incidence with the advent of HIV-AIDS. The authors report a case of vertebra-medullar histoplasmosis mimicking tuberculous spondylodiscitis in a patient without proven immunosuppression. This was a patient who spent 3 years in a highly endemic area. He presented with signs of transverse myelitis. MRI of the lumbar spine showed a para-vertebral tumor lesion that partially infiltrated the spinal cord. The positive diagnosis of histoplasmosis was made by histomorphology, and symptoms were reduced with administration of itraconazole. These findings show the need for a proper coding of the management of patients living or having stayed in histoplasmosis endemic areas, whether they are immunocompromised or not.
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