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  • Title: Increase in invasive group A streptococcal (Streptococcus pyogenes) infections (iGAS) in young children in the Netherlands, 2022.
    Author: de Gier B, Marchal N, de Beer-Schuurman I, Te Wierik M, Hooiveld M, ISIS-AR Study GroupMembers of the ISIS-AR Study Group are listed under Collaborators., GAS Study groupMembers of the GAS Study Group are listed under Collaborators., de Melker HE, van Sorge NM, Members of the GAS study group, Members of the ISIS-AR study group.
    Journal: Euro Surveill; 2023 Jan; 28(1):. PubMed ID: 36695447.
    Abstract:
    In 2022, a sevenfold increase in the number of notifiable invasive Streptococcus pyogenes (iGAS) infections among children aged 0-5 years was observed in the Netherlands compared with pre-COVID-19 pandemic years. Of 42 cases in this age group, seven had preceding or coinciding varicella zoster infections, nine were fatal. This increase is not attributable to a specific emm type. Vigilance for clinical deterioration as iGAS sign is warranted in young children, especially those with varicella zoster infection.
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