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  • Title: Non-random distribution of Alu-family repeats in human chromosomes.
    Author: Filatov LV, Mamayeva SE, Tomilin NV.
    Journal: Mol Biol Rep; 1987; 12(2):117-22. PubMed ID: 3670286.
    Abstract:
    A phage lambda recombinant clone containing at least 8 Alu-family repeats (AFRs) has been isolated from a human genomic library, and DNA from the phage was used as a probe for in situ hybridization on G-banded human metaphase chromosomes of healthy donors and leukemic patients. Some chromosome bands show prominent clusters of silver grains in all individuals examined: 1p34, 1q23, 2q21-22, 10p14, 11p14, 10q21 and 11q14. The data suggest non-random distribution of AFRs in the human genome.
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