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  • Title: [Preparations of acetylsalicylic acid sustained-release tablets on hydrophilic matrix forms].
    Author: Süss W, Bruder K.
    Journal: Pharmazie; 1987 Jul; 42(7):457-8. PubMed ID: 3671471.
    Abstract:
    The aim of this study was to prepare a tablet with acetylsalicylic acid based on hydrophilic matrix form by means of polyvinyl alcohol. The liberation was carried out with the column dissolution-rate method. In contrast to other studies, the percentage of the cumulative liberation is decreased by increasing the drug concentration. Acetylsalicylic acid caused a decrease of the wetting and the rate of swelling.
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