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  • Title: [Changes in the secondary structure of collagen after gamma-irradiation in an aqueous solution].
    Author: Duzhenkova NA, Klimova TP.
    Journal: Radiobiologiia; 1987; 27(5):594-9. PubMed ID: 3671675.
    Abstract:
    The conformation of calf skin collagen at the secondary structure level changed after 60Co-gamma-radiation with doses ranging from 50 to 1,000 Gy in aerated aqueous solutions and in the presence of N2 and N2O. Despiralization of collagen at a dose of 1,000 Gy reached 90% in N2O, 70% in N2, and 60% in the aerated solution. The radiochemical yield of the despiralized collagen molecules was 0.007 mol/100 eV owing to OH(.). The presence of radioprotective agents upon irradiation of collagen solutions diminished considerably the injury to its secondary structure.
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