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  • Title: Detection of impaired gas exchange using the 1-minute sit-to-stand test in patients with interstitial lung disease.
    Author: Oishi K, Asami-Noyama M, Yamamoto T, Matsumori K, Yonezawa K, Watanabe M, Hisamoto Y, Fukatsu A, Matsuda K, Hamada K, Suetake R, Ohata S, Murata Y, Yamaji Y, Sakamoto K, Ito K, Osoreda H, Edakuni N, Kakugawa T, Hirano T, Matsunaga K.
    Journal: Respir Investig; 2023 Mar; 61(2):186-189. PubMed ID: 36724582.
    Abstract:
    BACKGROUND: Although pulmonary function tests (PFTs) are important in patients with interstitial lung disease (ILD), they cannot be easily performed in a primary healthcare setting. This study aimed to examine the usefulness of the difference between pulse oxygen saturation (SpO2) at rest and the lowest SpO2 during the 1-min sit-to-stand test (delta SpO2-1STST) for predicting pulmonary function impairment. METHODS: We retrospectively reviewed 116 patients with ILD who underwent 1STST and PFTs. RESULTS: The delta SpO2-1STST and diffusing capacity for carbon monoxide (DLco) strongly correlated (ρ = 0.70). The delta SpO2-1STST was effective in predicting impaired gas exchange (cut-off value, -4%; AUC, 0.86; sensitivity, 74%; specificity, 87%). CONCLUSIONS: The Delta SpO2-1STST may be a reasonable tool for predicting abnormalities in PFTs.
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