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  • Title: Briastecholide M, a New Polyoxygenated Briarane from Briareum stechei.
    Author: Huynh TH, Wen ZH, Su JH, Yao ZK, Zheng LG, Tsai YC, Tanaka J, Liaw CC, Sung PJ.
    Journal: Chem Pharm Bull (Tokyo); 2023; 71(2):183-187. PubMed ID: 36724981.
    Abstract:
    A formerly unpublicized briarane diterpenoid, briastecholide M (1), and its established analogue, brianodin B (2), were purified from Briareum stechei, an octocoral collected from Okinawan waters. Using spectroscopic methods, the structure of 1 was established. Functional study showed that 1 can reducing the release of inducible nitric oxide synthase (iNOS) but enhancing cyclooxygenase-2 (COX-2) protein expression.
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