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  • Title: [A case of caseous calcification of mitral annulus resulting in multiple cerebral infarctions].
    Author: Ogasawara Y, Mano K, Henmi F, Uesaka Y, Takazawa Y.
    Journal: Rinsho Shinkeigaku; 2023 Feb 25; 63(2):97-100. PubMed ID: 36725008.
    Abstract:
    The patient is a 73-year-old woman. She presented with dysarthria, and a head MRI revealed multiple acute cerebral infarctions in the bilateral cerebral hemisphere and cerebellar hemisphere. Transesophageal echocardiography after admission revealed a 16 mm large mobile calcification of the mitral annulus (caseous calcification of the mitral annulus; CCMA) on the posterior apex of the mitral valve annulus. Since the CCMA had a high risk of relapse, and a new infarction was detected on the 8th day, resection of the mass and mitral valve replacement surgery were performed. CCMA is a subtype of mitral annular calcification (MAC). When calcification progresses from the MAC state to form a mass, it is called a calcified amorphous tumor; CAT. Reports of embolic cerebral infarction caused by CAT are rare, but this is a rare report of an embolic cerebral infarction from CCMA presenting as CAT.
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