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  • Title: [Does prolonging the test period improve screening for colorectal cancer?].
    Author: Hammes PH, Gnauck R.
    Journal: Z Gastroenterol; 1987 Sep; 25(9):607-11. PubMed ID: 3673146.
    Abstract:
    Prolongation of Haemoccult-screening from 3 to 6 days in 3540 out-patients resulted in a rise of the positivity rate from 4.1 to 6.75%. This was accompanied by an increase of the detection rate by 10% in cancers and 25% in large adenomas. The predictive value of a positive test for colorectal neoplasia (carcinoma and large polyps together) dropped from 26.7 to 20.9%. More data are needed before general recommendation for change from the standard 3-day-test period can be given.
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