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  • Title: V̇O2 (non-)linear increase in ramp-incremental exercise vs. V̇O2 slow component in constant-power exercise: Underlying mechanisms.
    Author: Korzeniewski B.
    Journal: Respir Physiol Neurobiol; 2023 May; 311():104023. PubMed ID: 36731708.
    Abstract:
    A computer model of the skeletal muscle bioenergetic system involving the Pi double-threshold mechanism of muscle fatigue was used to study the V̇O2 (non-)linear increase in time in ramp-incremental exercise as compared to the V̇O2 slow component in constant-power exercise. The Pi double-threshold mechanism applies to both constant-power and ramp-incremental exercise. The additional ATP usage is initiated at a significantly higher ATP usage activity (power output), determining the moderate/heavy exercise border, in ramp-incremental, than in constant-power exercise. A significantly lowered additional ATP usage activity or elevated glycolysis stimulation at the highest power outputs in ramp-incremental exercise in relation to constant-power exercise can additionally explain the much smaller (or zero) V̇O2 non-linearity in ramp-incremental exercise, than V̇O2 slow component in constant-power exercise. The V̇O2 (non-)linearity in ramp-incremental exercise and V̇O2 slow component in constant-power exercise is a derivative of a balance between the additional ATP usage and ATP production by anaerobic glycolysis.
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