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  • Title: An evaluation of Newcastle disease virus spray vaccination programs of market turkeys.
    Author: Kelleher CJ, Halvorson DA, Newman JA.
    Journal: Avian Dis; 1987; 31(3):431-7. PubMed ID: 3675421.
    Abstract:
    Commercial market turkeys that were spray-vaccinated at 2 to 3 weeks of age with viable Newcastle disease virus (NDV) vaccine usually did not develop high or persistent levels of serum antibody as detected by the hemagglutination-inhibition test. Vaccinated turkeys exhibited a satisfactory level of resistance to infection and clinical disease when challenged by the oculonasal or aerosol route at 2 weeks post-vaccination, and they resisted clinical disease when challenged at 6 weeks, but the level of protection diminished by 10 weeks post-vaccination. It is suggested that market turkeys produced in an NDV-enzootic area may require two or more NDV vaccinations by spray during their growing period in order to be adequately protected against natural NDV infection.
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