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Title: Coronary capillary permeability and tissue volumes for sucrose and water in dogs: a comparison of bolus and constant infusion multiple-indicator methods. Author: Harris TR, Burks DD, Custer PL. Journal: Cardiovasc Res; 1978 Sep; 12(9):537-46. PubMed ID: 367598. Abstract: This study was undertaken to determine the accuracy with which heart interstitial and water volumes could be determined from multiple-indicator dilution experiments on the coronary circulation in open-chest dog preparations. Sucrose permeability by extraction calculations was found to average 0.26 +/- 0.02 cm3 . (min . g tissue)-1. The extravascular sucrose volume averaged 0.15 cm3 . g-1 tissue by both multiple-indicator and post-mortem methods. Indicator-dilution tritiated water curves labelled 85% of the post-mortem water content.[Abstract] [Full Text] [Related] [New Search]