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  • Title: Freeze-fracture electron microscopic observations on the effects of sulphydryl group reagents on human erythrocyte membranes.
    Author: Benga G, Brain A, Pop VI, Hodarnau A, Wrigglesworth JM.
    Journal: Cell Biol Int Rep; 1987 Sep; 11(9):679-87. PubMed ID: 3677180.
    Abstract:
    Freeze-fracture electron microscopy of human red blood cells at pH 7.4 and 5.5 reveals the presence of membrane elevations (50-100 nm diameter). These are also observed after incubation of the erythrocytes with N-ethylmaleimide but not after incubation with p-chloromercuribenzene sulphonate. Neither of the sulphydryl-group reagents affects the distribution or size of intramembrane particles. The findings are discussed in the light of the effects of mercurials on erythrocyte membrane proteins.
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