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  • Title: In-vitro fertilization results from thirteen women with anti-sperm antibodies.
    Author: De Almeida M, Herry M, Testart J, Belaisch-Allart J, Frydman R, Jouannet P.
    Journal: Hum Reprod; 1987 Oct; 2(7):599-602. PubMed ID: 3680490.
    Abstract:
    Thirteen infertile women with high titres of spermagglutinating antibodies in their serum and/or in cervical mucus underwent in-vitro fertilization (IVF) and embryo transfer (ET). Fertilization occurred in 68% of the oocytes in a serum-free medium. Eight pregnancies were obtained in 22 IVF cycles (36.4%). Anti-sperm antibodies were found in the follicular fluids of 5 out of the 11 women with circulating antibodies. Fertilization results were independent of both the localization and the level of anti-sperm antibodies. From these data we can conclude that IVF-ET is a suitable treatment for long lasting female infertility linked to anti-sperm immunity.
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