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  • Title: Single-institution outcomes after excision of benign phyllodes tumors: low recurrence risk even with positive margins.
    Author: Balogun Z, Steiman JG, Schwartz JL, Lee JS, Soran A, Johnson RR, McAuliffe PF, Diego EJ.
    Journal: Breast Cancer Res Treat; 2023 Apr; 198(3):569-572. PubMed ID: 36807012.
    Abstract:
    PURPOSE: Benign phyllodes tumors (BPT) are rare breast neoplasms with clinical behavior that poses low recurrence risk. Guidelines regarding appropriate margins recommend surgical excision to negative margins, sometimes requiring re-excision surgery. Contemporary experience suggests that re-excision in the face of positive margins may not be needed. METHODS: This is a retrospective review of a single-institution experience with BPT from 2010 to 2019 with 102 patients. Demographics, outcomes and follow-up were analyzed. RESULTS: The median age was 37 years. 95% had a pre-operative biopsy and only 6% were confirmed BPT before surgery.56% had positive margins and were more likely to be younger and have a pre-operative diagnosis of fibroadenoma. The median follow-up was 33 months. Between the positive and negative margin groups, recurrence rates were not significantly different (p = 0.87). CONCLUSION: Positive margins on excision of BPT poses a low recurrence risk and re-excision surgery is not necessary.
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