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  • Title: A rare case of Klippel-Trenaunay syndrome presenting with chronic myeloid leukemia.
    Author: Coşkun Ç, Aksu T, Gümrük F, Ünal Ş.
    Journal: Turk J Pediatr; 2023; 65(1):124-128. PubMed ID: 36866992.
    Abstract:
    BACKGROUND: Klippel-Trenaunay syndrome (KTS) is an overgrowth syndrome associated with capillary/venous/ lymphatic malformations with limb hypertrophy and cancer risk. Various cancers, mostly Wilms tumor, have been reported in patients with KTS, but not leukemia. Chronic myeloid leukemia (CML) is also a rare disease in children, where there is no known disease or syndrome to predispose to CML. CASE: We report a case of CML incidentally diagnosed in a child with KTS when he was bleeding from surgery of the left groin for vascular malformation. CONCLUSIONS: This case reflects the variety of cancer types that may accompany KTS and provides information about CML prognosis in such patients.
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