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  • Title: [Structure of the blood microcirculatory bed in intramural uterine myomas].
    Author: Sapozhnikov AG.
    Journal: Vopr Onkol; 1987; 33(10):43-8. PubMed ID: 3686907.
    Abstract:
    Histological, morphometric and histochemical examination of uterine samples was carried out in 33 cases of intramural myoma (aged 26-45) and 32 autopsied controls with unaltered uterus (20-45 years). Peripheral areas of myomas showed a polymeric-homonomous structure of the blood microcirculatory bed. However, it was characterized by higher specific volumes of all components as compared to controls. This, perhaps, may account for local circulatory hyperestrogenism which supports myoma progression. Pronounced changes in the structure of microvessels of the central areas were matched by a 2-4-fold decrease in their specific volumes. The degree of said alteration in other areas of the myometrium was found to be in direct correlation with the size of myoma.
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