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  • Title: [Use of streptokinase and urokinase in deep venous thrombosis and pulmonary embolism: indications and clinical experience].
    Author: Scheffler P, Donecke P, de la Hamette D, Berberich R, Kramann B, Wenzel E.
    Journal: Z Gesamte Inn Med; 1987 Sep 01; 42(17):492-8. PubMed ID: 3687140.
    Abstract:
    The efficacy of fibrinolysis in DVT is dependent upon the age and organization of the thrombus as well as its localization. In consequence, selective evaluation prior to determining the indication for thrombolytic therapy is just as important for therapeutic success as choosing the appropriate fibrinolytic agent. To improve the results of fibrinolysis a team of angiologists, hemostaseologists, radiologists and surgeons are cooperating in a special "thromboembolic care unit". Phlebographic criteria were defined which allow differentiation of fibrinolytic indications depending upon the site of the thrombus. Selection of the fibrinolytic agent and careful monitoring of the thrombolysis should ensure a maximum therapeutic effect with a minimum of bleeding complications. The duration of thrombolysis was established through phlebographic verification and functional tests with venous occlusion plethysmography. The cause and results of 108 cases of thrombolysis shall be presented.
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