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  • Title: Effect of chloroquine on biliary lipid and lysosomal enzyme output in the isolated perfused rat liver at low bile salt output rates.
    Author: Rahman K, Coleman R.
    Journal: Biochim Biophys Acta; 1987 Dec 14; 922(3):395-7. PubMed ID: 3689819.
    Abstract:
    Chloroquine, when introduced into isolated perfused rat livers, caused a substantial output of cholesterol into bile, occurring after 30 min and peaking at 60 min, whereas the biliary output of acid phosphatase and beta-glucuronidase increased only after 90 min. The origins of this bile-salt-independent cholesterol are discussed.
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