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  • Title: Subtle actions of 2-amino-4-phosphonobutyrate (APB) on the Off pathway in the mudpuppy retina.
    Author: Arkin MS, Miller RF.
    Journal: Brain Res; 1987 Nov 17; 426(1):142-8. PubMed ID: 3690311.
    Abstract:
    The principal action of 2-amino-4-phosphonobutyrate (APB) applied to the retina is the elimination of the On-bipolar cell light response. In this study, we report that APB also has more subtle effects; it sometimes enhances Off responses of Off bipolar cells and On, Off, and On-Off inner retina neurons. Possible mechanisms for this enhancement are considered.
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