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  • Title: [Peripheral neuropathy in severe mixed cryoglobulinemia syndrome].
    Author: Thenint JP, Penniello MJ, Chapon F, Viader F, Beaudoin A, Morin P.
    Journal: Can J Neurol Sci; 1987 Nov; 14(4):581-5. PubMed ID: 3690428.
    Abstract:
    A syndrome of polyneuropathy and cryoglobinemia is reported in a 76-year-old woman. Nerve biopsy showed severe demyelination and vascular involvement was demonstrated in a muscle biopsy. Peripheral neuropathy is discussed in the context of the Gougerot-Sjögren syndrome, associated with cryoglobins in the blood. Prompt treatment of this disease should be initiated and consists mainly of plasmapheresis.
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