These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Risk of Hypercalcemia in the Elderly Patients with Hypervitaminosis D and Vitamin D Intoxication.
    Author: Calim A.
    Journal: Clin Lab; 2023 Mar 01; 69(3):. PubMed ID: 36912306.
    Abstract:
    BACKGROUND: We aimed to evaluate the risk of hypercalcemia in the elderly population with hypervitaminosis D and vitamin D intoxication. METHODS: A total of 121 patients with a 25(OH) vitamin D level > 100 ng/mL from patients aged ≥ 65 years who applied to our hospital between 2014 and 2020 were included in this study. Sixty-nine patients with 25(OH) vitamin D levels of 100 - 150 ng/mL were determined as D hypervitaminosis; 52 patients with 25(OH) vitamin D levels > 150 ng/mL were determined as vitamin D intoxication. People with a calcium level above 10.2 mg/dL were considered as hypercalcemic patients. RESULTS: Of 121 patients with D hypervitaminosis and vitamin D intoxication, 103 (85.1%) were normocalcemic, and 18 (14.9%) were hypercalcemic. Hypercalcemia was detected in 9 out of 69 patients with hypervitaminosis D; 8 of them had mild hypercalcemia and 1 person had severe hypercalcemia. Hypercalcemia was detected in 9 of 52 patients with vitamin D intoxication; mild hypercalcemia was found in 7 people, moderate hypercalcemia in 1 person, severe hypercalcemia in 1 person. There was no statistically significant difference between the incidence of hypercalcemia in patients with D hypervitaminosis and vitamin D intoxication (p = 0.514). It was observed that a total of 3 (16.7%) of the hypercalcemic patients with D hypervitaminosis and vitamin D intoxication died. CONCLUSIONS: In the elderly population with hypervitaminosis D and vitamin D intoxication, most of the patients were seen as normocalcemic. However, severe hypercalcemia, which was life-threatening and resulted in death, was also observed. Using vitamin D in elderly patients should be performed according to the guideline recommendations. Calcium level and clinical findings should be checked during follow-up.
    [Abstract] [Full Text] [Related] [New Search]