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  • Title: Surgery in combined pulmonary and neural cryptococcosis.
    Author: Sa'adah MA, Shakir RA, Jadaa SI, Bezjak V, Araj GF.
    Journal: J Infect; 1987 Nov; 15(3):263-8. PubMed ID: 3693927.
    Abstract:
    A 39-year-old previously healthy patient with combined pulmonary and neural cryptococcosis was successfully managed by pulmonary resection and antifungal chemotherapy. The pulmonary mass was removed under cover of miconazole and 5-fluorocytosine even though the patient had concomitant active meningitis. He recovered dramatically after the surgical procedure and remained well 2 years later. We suggest that, as in our patient, early removal of a pulmonary cryptococcal mass under antifungal cover may in other similar patients obviate the need for protracted antifungal therapy and lead to an excellent response of the neural cryptococcosis.
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