These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Characterization of an Escherichia coli K12 mutant that is sensitive to chlorate when grown aerobically.
    Author: Giordano G, Grillet L, Rosset R, Dou JH, Azoulay E, Haddock BA.
    Journal: Biochem J; 1978 Nov 15; 176(2):553-61. PubMed ID: 369552.
    Abstract:
    Escherichia coli can normally grow aerobically in the presence of chlorate; however, mutants can be isolated that can no longer grow under these conditions. We present here the biochemical characterization of one such mutant and show that the primary genetic lesion occurs in the ubiquinone-8-biosynthetic pathway. As a consequence of this, under aerobic growth conditions the mutant is apparently unable to synthesize formate dehydrogenase, but can synthesize a Benzyl Viologen-dependent nitrate reductase activity. The nature of this activity is discussed.
    [Abstract] [Full Text] [Related] [New Search]