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  • Title: Extraosseous uptake of technetium-99m MDP in secondary deposits of neuroblastoma.
    Author: Mandell GA, Heyman S.
    Journal: Clin Nucl Med; 1986 May; 11(5):337-40. PubMed ID: 3698433.
    Abstract:
    Extraosseous uptake of radiophosphate compounds i well recognized in primary neural crest tumors. In a review of 32 cases of neuroblastoma presenting over a three-year period at Children's Hospital of Philadelphia, nine patients were noted to have secondary lesions in eleven different sites accumulating radiotracer. The extraosseous uptake in metastases included: ascites, liver, lung, anterior mediastinum, and posterior mediastinum. These cases are reported to emphasize the ability of bone imaging to detect the presence of extraosseous soft tissue metastases and primary lesions.
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