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  • Title: Responses of serotonergic and non-serotonergic neurons in the rat nucleus raphe magnus to systemic lysergic acid diethylamide.
    Author: Wei JB, Chiang CY.
    Journal: Neurosci Res; 1986 Feb; 3(3):268-73. PubMed ID: 3703384.
    Abstract:
    Serotonergic and non-serotonergic neurons in the nucleus raphe magnus were identified by conduction velocities and spontaneous discharge rates. Eight of 13 serotonergic neurons were depressed by lysergic acid diethylamide (LSD) administration (40-50 micrograms/kg, i.p. or i.v.), while the others were non-responsive. Among 38 non-serotonergic neurons, 5 were depressed, 4 were excited and 29 were unaffected by systemic LSD at the same doses. It is thus concluded that LSD could act differently on serotonergic and non-serotonergic neurons in nucleus raphe magnus.
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