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  • Title: [Diagnostic value of radionuclide visualization of the reticuloendothelial system of macrophages in multiple sclerosis].
    Author: El'chaninov AP, Artiushkin AV, Skoromets AA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1986; 86(2):200-3. PubMed ID: 3705822.
    Abstract:
    Scintigraphic examination of the liver, spleen, bone marrow and retroperitoneal lymph nodes with the help of colloidal radiopharmaceutical 113mIn was conducted in 55 patients with multiple sclerosis (MS) and in 13 patients with other diseases of the nervous system. The authors ascertained dysfunction of cells of the mononuclear phagocytic system (MPS) in the MS patients. Clinical manifestations of the disease were found to correlate with the findings of radionuclide imaging of the parenchymatous organs and lymph nodes. A conclusion was drawn about the total disruption of the functional activity of MPS cells in MS and the inevitable involvement of the liver in the pathogenesis of the disease.
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