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  • Title: [Long-term moditen-depot treatment of schizophrenic patients at a psychoneurology dispensary].
    Author: Abramova LI, Gushanskiĭ EL.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1986; 86(3):419-24. PubMed ID: 3705854.
    Abstract:
    In 31 patients with paroxysm-like progressive and 19 with continuously progressive paranoid schizophrenia the authors examined the results of long-term (from 4 to 11 years) treatment with moditen depot. The mean dosage of the drug was 25-50 mg per 3-4 weeks. A good therapeutic response was observed in more than half the cases. In group I patients it was expressed in the absence of relapses, improvement of quality and increase in the duration of the remissions; in group II it was expressed in an increased tendency toward a regressing course with a reduced intensity of processional manifestations. A favourable effect was accompanied by improved social and occupational adaptation of patients.
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