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  • Title: Primary chronic abortion, preeclampsia, idiopathic intrauterine growth retardation, hydatidiform mole, and choriocarcinoma: a unifying concept.
    Author: Labarrere CA, Althabe OH.
    Journal: Am J Reprod Immunol Microbiol; 1986 Apr; 10(4):156-7. PubMed ID: 3706608.
    Abstract:
    Different degrees of maternal hyporesponse, as far as blocking activity is concerned, are proposed for primary chronic abortion, preeclampsia, and idiopathic intrauterine growth retardation. On the other hand, a maternal hyperresponse to fetal antigens with a higher production of blocking antibodies may be related to an unusual proliferation of the trophoblast in cases of hydatidiform mole and choriocarcinoma.
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