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  • Title: [Allergologic study of allergic asthma and therapeutic implications].
    Author: Ségalen C.
    Journal: Ann Med Interne (Paris); 1986; 137(1):17-20. PubMed ID: 3706955.
    Abstract:
    The diagnosis of allergic asthma is based on a number of clinical and paraclinical findings which should allow the appropriate therapeutic decisions to be taken. The following diagnostic procedures are available to the clinician: the clinical history which is always of prime importance, skin tests, second stage of diagnosis, total serum and specific IgE (RAST) concentrations demonstrate an IgE dependent mechanism, the human basophil degranulation test (HBDT) to assess cellular sensitivity, bronchial or nasal provocation tests which finally demonstrate the responsibility of the causative allergen. In practice, the clinical history, skin tests and the RAST are sufficient to establish the diagnosis of allergy and to take the appropriate therapeutic measures: eviction, antidegranulation therapy or specific immunotherapy.
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